I have had similar questions over the years (25+) and found out early on that "taking the easy way is not always the best way". In other words, like anyone else "I WANT IT ALL AND I WANT IT NOW!" =0) But, with some guidance, study, and time you can "get it"...
Okay, lets get started!
Since you used "the E blues scale" as an example, lets talk about it...
Chords are derived from scales. So lets take a look at the notes of the E blues scale:
Having had similar questions myself, I learned everything I could about chord theory. Using the notes of the E blues scale, from experience with chords, I can see all of the notes that make an Em chord (E-G-B), so that chord would be a definite must have. I also see an Em7 (just the notes of an Em + a D note). I also see a few "power chords" in the scale also, an E5 chord (E-B), an A5(A-E), also G5 (G-D). I can also see a G major (G-B-D) & minor (G-Bb-D)...
I hope this is not too confusing. Maybe just this little bit of nfo can get you started seeing the possibilities of chords & scales.